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Last updated: Aug 9, 2026

Domino's

Spicy Buffalo 5-Cheese Mac & Cheese Penne Pasta

Penne PastaPopular

Domino's Spicy Buffalo 5-Cheese Mac & Cheese Penne Pasta is fat-leaning, with about 54% of macro calories from fat. Each serving has 840 calories, 31g protein, 64g carbs, and 50g fat, making it better suited to carb-aware planning than low-carb goals.

1 dish (374g)

Serving Size

374 g

Serving Weight

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840

Calories

Per serving

31 g

Protein

64 g

Carbs

50 g

Fat

Nutrition Facts

Amount per serving

Calories840 kcal

% Daily Value*

Total Fat 50 g64%

Saturated Fat 31 g155%

Trans Fat 1.5 g—

Cholesterol 145 mg48%

Sodium 2,090 mg91%

Total Carbohydrate 64 g23%

Dietary Fiber 2 g7%

Total Sugars 6 g—

Protein 31 g62%

Vitamin A—

Vitamin C—

Vitamin D—

Calcium—

Iron—

Potassium—

Caffeine—

* The % Daily Value tells you how much a nutrient in a serving contributes to a daily diet.

Nutrition Breakdown

840

kcal

Protein31 g (15%)

Carbs64 g (31%)

Fat50 g (54%)

Estimated calorie contribution using 4 kcal/g for protein and carbohydrates and 9 kcal/g for fat.

Meal Planning Insights

Protein density3.7/10

15% of macro calories come from protein.

Satiety index10/10

Estimated from protein, fiber, calories, and fat balance.

Activity estimate210 min walk

About 84 minutes of running for these calories.

Key Nutrients

Protein 31 g62%

Fiber 2 g7%

Sodium 2,090 mg91%

Sugars 6 g—

Saturated Fat 31 g155%

How we calculate these values

Diet Compatibility

High protein3.7/10 protein density from 31g protein and 840 calories.No

Lower carb64g carbs per serving.No

Low fat50g total fat per serving.No

High sugar6g total sugars per serving.No

High sodium2,090mg sodium per serving.Yes

Vegetarian source flagNo vegetarian flag is published for this item.Not flagged

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5-Cheese Mac & Cheese Penne Pasta830 kcal · 30 g protein

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Quick comparisons

Spicy Buffalo 5-Cheese Mac & Cheese Penne Pasta has 10 more calories than 5-Cheese Mac & Cheese Penne Pasta and 1g more protein. Compare

Spicy Buffalo 5-Cheese Mac & Cheese Penne Pasta has 800 more calories than Alfredo Sauce, Portion for Extra Large Hand Tossed Pizza and 30g more protein. Compare

5-Cheese Mac & Cheese Penne Pasta830 kcal · 30 g proteinAlfredo Sauce, Portion for Extra Large Hand Tossed Pizza40 kcal · 1 g proteinAlfredo Sauce, Portion for Extra Large New York Style Pizza50 kcal · 1 g proteinAlfredo Sauce, Portion for Extra Small Hand Tossed Pizza30 kcal · 1 g proteinAlfredo Sauce, Portion for Large Hand Tossed or Crunchy Thin Crust Pizza30 kcal · 1 g proteinAlfredo Sauce, Portion for Large New York Style Pizza45 kcal · 1 g protein

Compare with 5-Cheese Mac & Cheese Penne Pasta

Spicy Buffalo 5-Cheese Mac & Cheese Penne Pasta Compared With Nearby Items

Compared with 5-Cheese Mac & Cheese Penne Pasta, another Penne Pasta item at Domino's, Spicy Buffalo 5-Cheese Mac & Cheese Penne Pasta has 10 more calories than it and 1g more protein than it. That makes this page useful for deciding between nearby menu choices, not just reading a raw nutrition label.

Data Source and Methodology

Nutrition values for Spicy Buffalo 5-Cheese Mac & Cheese Penne Pasta are maintained in Nutrimetry from restaurant-published menu data and were last checked on Aug 9, 2026. Macro percentages use 4 calories per gram for protein and carbohydrates and 9 calories per gram for fat.

Read the data methodology

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