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Last updated: Aug 9, 2026

Papa John's

Pepperoni, Sausage & Six Cheese Pizza, Original Crust, Large

Specialty PizzasPopular

Papa John's Pepperoni, Sausage & Six Cheese Pizza, Original Crust, Large is fat-leaning, with about 46% of macro calories from fat. Each serving has 390 calories, 16g protein, 36g carbs, and 20g fat, making it a moderate option for comparing calories and macros.

1 slice

Serving Size

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390

Calories

Per serving

16 g

Protein

36 g

Carbs

20 g

Fat

Nutrition Facts

Amount per serving

Calories390 kcal

% Daily Value*

Total Fat 20 g26%

Saturated Fat 9 g45%

Trans Fat 0 g—

Cholesterol 45 mg15%

Sodium 920 mg40%

Total Carbohydrate 36 g13%

Dietary Fiber 1 g4%

Total Sugars 3 g—

Protein 16 g32%

Vitamin A—

Vitamin C—

Vitamin D—

Calcium—

Iron—

Potassium—

Caffeine—

* The % Daily Value tells you how much a nutrient in a serving contributes to a daily diet.

Nutrition Breakdown

390

kcal

Protein16 g (16%)

Carbs36 g (37%)

Fat20 g (46%)

Estimated calorie contribution using 4 kcal/g for protein and carbohydrates and 9 kcal/g for fat.

Meal Planning Insights

Protein density4.1/10

16% of macro calories come from protein.

Satiety index9.3/10

Estimated from protein, fiber, calories, and fat balance.

Activity estimate98 min walk

About 39 minutes of running for these calories.

Key Nutrients

Protein 16 g32%

Fiber 1 g4%

Sodium 920 mg40%

Sugars 3 g—

Saturated Fat 9 g45%

How we calculate these values

Diet Compatibility

High protein4.1/10 protein density from 16g protein and 390 calories.No

Lower carb36g carbs per serving.No

Low fat20g total fat per serving.No

High sugar3g total sugars per serving.No

High sodium920mg sodium per serving.Yes

Vegetarian source flagNo vegetarian flag is published for this item.Not flagged

Compare with other items

Select up to 3 items to compare calories, protein, sodium, and macros.

Quick comparisons

Pepperoni, Sausage & Six Cheese Pizza, Original Crust, Large has 620 fewer calories than A&W Cream Soda, 2 Liter and 16g more protein. Compare

Pepperoni, Sausage & Six Cheese Pizza, Original Crust, Large has 90 more calories than A&W Cream Soda, 20 Oz and 16g more protein. Compare

A&W Cream Soda, 2 Liter1,010 kcal · 0 g proteinA&W Cream Soda, 20 Oz300 kcal · 0 g proteinA&W Root Beer, 2 Liter1,010 kcal · 0 g proteinA&W Root Beer, 20 Oz300 kcal · 0 g proteinAMP, 16 Oz220 kcal · 1 g proteinAlfredo Sauce for Gluten Free Crust10 kcal · 0 g protein

Compare with A&W Cream Soda, 2 Liter

Pepperoni, Sausage & Six Cheese Pizza, Original Crust, Large Compared With Nearby Items

Papa John's Pepperoni, Sausage & Six Cheese Pizza, Original Crust, Large is listed in the Specialty Pizzas category with 390 calories, 16g protein, 36g carbs, and 20g fat per serving.

Data Source and Methodology

Nutrition values for Pepperoni, Sausage & Six Cheese Pizza, Original Crust, Large are maintained in Nutrimetry from restaurant-published menu data and were last checked on Aug 9, 2026. Macro percentages use 4 calories per gram for protein and carbohydrates and 9 calories per gram for fat.

Read the data methodology

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